Polymer-Clay Nanotube Biocomposites with Sustained Drug Release
演讲嘉宾:Prof. Yuri Lvov (美国路易斯安那理工大学)
职 位:微技术制造学院副主任、T. Pipes荣誉主席
演讲主持:闫学海 研究员
演讲时间:2014年9月26日(星期五)10:00-11:00
演讲地点:生化楼一层会议室
主 办:生物材料过程工程团队
嘉宾简介(C.V.)
Dr. Yuri Lvov is a Professor of Chemistry, Tolbert Pipes Eminent Endowed Chair on Micro and Nanosystems and Associate Director of the Institute for Micromanufacturing, Louisiana Tech University. His area of specialization is nanotechnology including nanoassembly of ultrathin organized films, bio/nanocomposites, nanoconstruction of ordered shells on tiny templates, and clay nanotubes for controlled release of bioactive agents.
He was among pioneers of the polyelectrolyte layer-by-layer (LbL) assembly, a nanotechnology method which, after his first papers in 1993, followed by many thousands publications by researchers all over the world. He edited three books, published 22 book chapters, and 214 peer reviewed papers on nanosystems. Lvov’s total citation index is above 12,800 which is an outstanding result, and his h-index is 57.
In 2003, 2008, 2011 and 2013 he chaired American Chemical Society (ACS) International Symposiums on Nanoassembly in New York, Philadelphia, Anaheim and New Orleans. He was named the Louisiana State’s Top Researcher in New Technologies (2007), and got Best of Small Tech National Innovator Award in recognition of achievements in micro and nanotechnology (2008). In 2013, Lvov was awarded with prestigious international A. von Humboldt Prize for achievements in chemistry.
Prof. Lvov has been invited to present talks at more than 140 international scientific conferences and has delivered lectures at more than 50 major universities. He was elected as a honorable professor of Beijing University of Chemical Technology, China and Kazan Federal University, Russia (2013).
报告简介(Introduction )
Natural halloysite clay nanotubes are described as inorganic reinforcing materials for polymers. Loading these tubes’ 15-nm diameter lumens with chemical agents, including bioactive molecules (proteins, DNA, drugs, etc.), and doping them into polymers allows a controlled sustained release, providing these nanocomposites with new smart properties. Typically, addition of 5% halloysite synergistically increases polymer strength on 30C70%, enhances composite adhesivity and adds new functions due to triggered release of needed chemicals. Halloysite is biocompatible ”green” material and its simple processing combined with low cost make it a perspective additive for polymeric biocomposites. Comparison of halloysite with other tubule clay Cimogolite C is given; these tubes have smaller diameter and much lower loading capacity for macromolecules.
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