报告题目：Constructing injectable hydrogels to rebuild heart function after myocardial infarction
报 告 人：王 玮 副教授
主 持 人：张 欣 研究员
报告摘要：
Previous researchers concluded that a stiffer hydrogel system exhibited a better performance to promote myocardium regeneration heart function after myocardial infarction (MI). However, by reconsidering the nature of myocardium, a tissue that is alternately contracting and relaxing with electrical impulses, we hypothesized that a soft and conductive hydrogel may be in favor of mechanical and electrical signals transmission to enhance heart function after myocardial infarction (MI). In this report, instead of rigid conductive polymers, π-π conjugation interaction was employed to produce an injectable hydrogel with conductive property. The hydrogel encapsulating adipose tissue-derived stromal cells (ADSCs) was injected into MI area of rats, and the results revealed that Meanwhile, a significant improvement of heart function was confirmed by the distinct increasing of ejection fraction (EF), smaller infarction size, less fibrosis area, and higher vessel density.
Dr. Wei Wang (王玮) is an Associate Professor of Tianjin University, China. He received his doctorate in June 2010 in Zhejiang University, China. He works in three fields, namely 1) tissue engineering scaffolds; 2) functional hydrogels for wound healing and myocardial infarction; 3) controlled/living polymerization techniques (ATRP and RAFT). He has published more than 40 peer-reviewed papers including Progress in Polymer Sciences, Advanced Materials, and Biomaterials, which have been cited more than 1200 times (H-index=15), which can be seen in the website: https://scholar.google.com/citations user=oCK-8zcAAAAJ&hl=zh-EN.
报告时间：2017年10月25日（星期三）上午11:00-12:00
报告地点：中国科学院过程工程研究所生化科研楼一层会议室
承办单位：生化工程国家重点实验室基因药剂型工程课题组
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