徐霞课题组

Xu Xia  Ph.D. 

课题组长、研究员

英国牛津大学博士学位（2004年）

Email：xuxia@ipe.ac.cn

研究领域

生物技术中生物活性物质的保存策略和应用研究

体外治疗技术

生物医药的使能技术

发表的主要论文（近5年）

[1] Yanqing Xu, Liang Zhang, Jiandong Xu, Yuping Wei, Xia Xu. Sensitivity of human embryonic stem cells to different conditions during   cryopreservation. Cryobiology, 2015, 71: 486-492.
[2] Yankai Fua,   Yanzhuo Wu, Yuping Wei, Xianhua Chen, Jiandong Xu, Xia Xu. Development of a thermally stable formulation for L-Asparaginase storage in aqueous   conditions. Journal of Molecular Catalysis B: Enzymatic, 2015, 122: 8-14.
[3] Yuping Wei, Jiandong Xu, Liang Zhang, Yankai Fu, Xia Xu.   Development of novel small peptide ligands for antibody purification. RSC Advances, 2015, 5: 67093-67101.
[4] Jiandong Xu, Xuefei Lv, Yuping Wei, Liang Zhang, Rui Li, Yulin Deng, Xia Xu. Air bubble resistant and disposable microPCR chip with a portable and pogrammable device for forensic test. Sensors and Actuators B: Chemical, 2015, 212: 472-480.
[5]Yanqing Xu, Liang Zhang, Jiandong Xu, Yuping Wei, Xia Xu. Membrane Permeability of the Human Pluripotent Stem Cells to Me2SO, Glycerol and 1,2-Propanediol. Archives of Biochemistry and Biophysics. 2014, 550–551: 67–76 
[6]Yuping Wei, Chunlong Li, Liang Zhang, Xia Xu. Design of Novel Cell Penetrating Peptides for the Delivery of Trehalose into Mammalian Cells, BBA Biomembrane. 2014, 1838: 1911-1920 
[7]Hongmei Liu, Yan Li, Anbu Mozhi, Liang Zhang, Yilan Liu, Xia Xu, Jianmin Xing, Xingjie Liang, Guanghui Ma, Jun Yang, Xin Zhang. SiRNA-phospholipid conjugates for gene and drug delivery in cancer treatment. Biomaterials. 2014, 35: 6519–6533 
[8]Yuping Wei, Chunlong Li, Liang Zhang, Zhiguo Su, Xia Xu. Inhibition of Methemoglobin Formation in Aqueous   Solutions under Aerobic Conditions by Addition of Amino Acids. International Journal of Biological Macromolecules. 2014, 64: 267-275
[9]Xia Xu, Yang Liu, ZhanFeng Cui. Effects of cryopreservation on human mesenchymal stem cells attached to different substrates. Journal of   Tissue Engineering and Regenerative Medicine. 2014, 8：664-672
[10]Xu Xia, Liu Yang, Cui Zhanfeng, Wei Yuping, Zhang Liang. Effects of osmotic and cold shock on adherent human mesenchymal stem cells during cryopreservation. Journal Biotechnology, 2012, 162: 224-31. 
[11]Xu   Xia, Liu Yang, Cui Zhanfeng, Effects of cryopreservation on human   mesenchymal stem cells attached to different substrates. Journal of   Tissue Engineering and Regenerative Medicine. 2012. DOI:   10.1002/term.1570
[12]Yang Liu, Xia Xu, Xuehu Ma, Zhanfeng Cui,   Effects of various freezing solutions on cryopreservation of mesenchymal   stem cells from different animal species. Cryoletter. 2011. 32: 367-376
[13]Sammy Sambu, Xia Xu, Hua Ye, Zhanfeng Cui. Predicting the   survival rate of mouse embryonic stem cells cryopreserved in alginate   beads. Journal of Engineering in Medicine. 2011. 225: 11 1092-1107 [14]Sammy Sambu, Xia Xu, HA Schiffter, ZF Cui and H Ye. RGDS-fuctionalized   alginates improve the survival rate of encapsulated embryonic stem cells   during cryopreservation. Cryoletters. 2011. 32: 389-401

授权发表专利（近5年） 

[1]徐霞，韦宇平，梅雪峰. 一种用于微小固体颗粒的流态化分选装置和方法. 中国发明专利，专利号：ZL201110053587.9
[2]徐霞，韦宇平。一种小分子抗体亲和肽及其应用。ZL201310178973.x
[3]徐霞，韦宇平。一种小分子抗体亲和肽及其应用。ZL201310208421.9
[4]徐霞，李春龙，韦宇平。一种新型穿膜肽及其应用。ZL201310085250.5
[5]徐建栋，徐霞。一种用于测量固体药物固有溶出度及溶出度的分析仪。ZL201310751343.7