苏志国课题组

Su Zhiguo  Ph. D.

课题组长、研究员

英国曼彻斯特大学博士学位（1985年）

Email: zgsu@ipe.ac.cn

研究领域

蛋白质药物的分子修饰

血液代用品

蛋白质折叠复性

超大生物分子的纯化及结构稳定

发表的主要论文（近5年）

[1] Xiaoyuan Ji, Zhiguo Su, Ping Wang, Guanghui Ma, Songpin Zhang.   Tethering of nicotinamide adenine dinucleotide inside hollow nanofibers   for high-yield synthesis of methanol from carbon dioxide catalyzed by   coencapsulated multienzymes. ACS Nano, 2015, 9 (4): 4600-4610. (IF   14.412)
[2] Hong Wu, Chunyong Tian, Yufei Zhang, Chen Yang,   Songping Zhang, Zhongyi Jiang. Stereoselective assembly of amino   acid-based metal-biomolecule nanofibers. Chemical Communications, 2015,   2015, 51: 6329-6332. (IF 6.779)
[3] Hong Wu, Chunyong Tian, Yufei   Zhang, Jiafu Shi, Songpin Zhang. Mask-like symmetrical microclusters   through a diffusion-limited assembly approach. Chemistry-A European   Journal, 2015, 21(28): 10185-10190. (IF 5.635)
[4] Yanli Yang,   Mengran Yu, Songpin Zhang, Guanghui Ma, Zhiguo Su. Adsorption of   virus-like particles on ion exchange surface: conformational changes at   different pH detected by dual polarization interferometry. Journal of   Chromatography A, 2015, 1408: 161-168. (IF 4.298)
[5] Mengran Yu,   Songpin Zhang, Yan Zhang, Yanli Yang, Guanghui Ma, Zhiguo Su.   Microcalorimetric study of adsorption and disassembling of virus-like   particles on anion exchange chromatography media. Journal of   Chromatography A, 2015, 1388:195-206. (IF 4.298)
[6] Liting Zhang,   Xiaodan Cao, Lu Wang, Xueyan Zhao, Songpin Zhang, Ping Wang. Printed   microwells with highly stable thin-film enzyme coatings for   point-of-care multiplex bioassay of blood samples. Analyst, 2015,   140:4105-4113. (IF 4.14)
[7] Yanli Yang, Hao Li, Zhengjun Li, Yan   Zhang, Songpin Zhang, Yi Chen, Mengran Yu, Guanghui Ma, Zhiguo Su.   Size-exclusion HPLC provides a simple, rapid, and versatile alternative   method for quality control of vaccines by characterizing the assembly of   antigens. Vaccine, 2015, 33(9): 1143-1150. (IF 3.338)
[8] Yi   Chen, Yan Zhang, Can Quan, Jian Luo, Yanli Yang, Mengran Yu, Yingjun   Kong, Guanghui Ma, Zhiguo Su. Aggregation and antigenicity of virus like   particle in salt solution-A case study with hepatitis B surface   antigen. Vaccine, 2015, 33(35): 4300-4306. (IF 3.338)
[9] Dawei   Zhao, Yongdong Liu, Guifeng Zhang, Chun Zhang, Xiunan Li, Qingqing Wang,   Hong Shi, Zhiguo Su. Interaction of arginine with protein during   refolding process probed by amide H/D exchange mass spectrometry and   isothermal titration calorimetry. Biochim Biophys Acta, 2015,   1854:39-45. (IF 3.127)
[10] Xiaoyu Yan, Yanjun Jiang, Songpin   Zhang, Jing Gao, Yufei Zhang. Dual-functional oph-immobilized polyamide   nanofibrous membrane for effective organophosphorus toxic agents   protection. Biochemical Engineering Journal, 2015, 98: 47-55. (IF 2.989)
[11]   Lijing Sun, Zhidong Xiong, Weiqing Zhou, Ruihua Liu, Xingran Yan, Juan   Li, Wenqi An,Yuan Guoqiang, Guanghui Ma, Zhiguo Su. Novel konjac   glucomannan microcarriers for anchorage-dependent animal cell culture.   Biochemical Engineering Journal, 2015, 96: 46-54. (IF 2.989)
[12]   Yan Zhang, Jian Luo, Songpin Zhang, Qian Bai, Zenglan Li, Qiang Li,   Yongdong Liu, Guifeng Zhang, Guanghui Ma, Zhiguo Su. Selection of   downstream steps by analysis of protein surface property: a case study   for recombinant human lactoferrin purification from transgenic milk.   Process Biochemistry, 2015, 50: 1441-1448. (IF 2.909)
[13] Chun   Zhang, Yongdong Liu, Cui Feng, Qi Wang, Hong Shi, Dawei Zhao, Rong Yu,   Zhiguo Su. Loss of PEG chain in routine SDS-PAGE analysis of   PEG-maleimide modified protein. Electrophoresis, 2015, 36 (2): 371-374.   (IF 2.723)
[14] Manfeng Deng, He Zhao, Songping Zhang, Chunyong   Tian, Di Zhang, Penghui Du, Chenming Liu, Hongbin Cao, Heping Li, Highly   catalytic activity of immobilized laccase on core-shell magnetic   nanoparticles by dopamine self-polymerization, Journal of Molecular   Catalysis B: Enzymatic, 2015, 112: 15-24. (IF 2.622)
[15] Shida   Miao, Kai Liu, Ping Wang, Zhiguo Su, Songping Zhang. Preparation and   characterization of epoxidized soybean oil-based paper composite as   potential water-resistant materials. Journal of Applied Polymer Science,   2015, 132(10): 41575-41583. (IF 1.662)
[16] Hao Li, Yanli Yang,   Yan Zhang, Songping Zhang, Qizu Zhao, Yuanyuan Zhu, Xingqi Zou, Mengran   Yu, Guanghui Ma, Zhiguo Su. A hydrophobic interaction chromatography   strategy for purification of inactivated foot and mouth disease virus.   Protein Expression Purification, 2015. 113: 23-29. (IF 1.617)
[17]   Xiunan Li, Yaqiong Chen, Chao Zhao, Dawei Wang, Xiaojun Zhao, Lan Shi,   Guanghui Ma, Zhiguo Su. Pore size analysis from low field NMR spin-spin   relaxation measurements of porous microspheres. Journal of Porous   Materials, 2015, 22(1): 11-13. (IF 1.343)
[18] Qingqing Wang, Tao   Hu, Lijing Sun, Shaoyang Jia, Dawei Zhao, Jiaxin Liu, Guanghui Ma,   Zhiguo Su. CO binding improves the structural, functional, physical and   anti-oxidation properties of the PEGylated hemoglobin. Artificial Cells   Nanomedicine and Biotechnology, 2015, 43(1): 18-25. (IF 1.015)
[19]   Kai Liu, Songping Zhang, Zhiguo Su, Guanghui Ma. Preparation and   characterization of castor oil-based cationic waterborne polyurethane.   Advanced Materials Research, 2015, 1090: 3-7.
[20] 冯翠，王祺，张纯，秦培勇，郑秀玉，王健，刘永东，苏志国，PEG 定点修饰重组人睫状神经营养因子及其生物活性评价，中国生物工程杂志，2015, 35 (5): 15-21。
[21] 李小连，王自强，王云山，董晓芳，张利平，苏志国，醋糟酶解液的制备及发酵生产枯草芽孢杆菌TS-02，过程工程学报，2015, 2: 86-92。
[22]Xiaoyuan   Ji, Zhiguo Su, Ping Wang, Guanghui Ma, Songping Zhang. Polyelectrolyte   doped hollow nanofibers for positional assembly of bi-enzyme system for   cascade reaction at O/W interface. ACS Catalysis. 2014, 4(12): 4548−455
[23]Shida   Miao, Ping Wang, Zhiguo Su, Songping Zhang. Vegetable oil-based   polymers as future polymeric biomaterials. Acta Biomaterialia. 2014,   10(4):1692–1704 (Invited review). 
[24]Xiaoyuan Ji, Ping Wang,   Zhiguo Su, Guanghui Ma, Songping Zhang. Enabling multienzyme   biocatalysis using coaxial-electrospun hollow nanofibers: redesign of   artificial cells. J Material Chemistry B. 2014, 2: 181-190 
[25]Xiaoyuan   Ji, Zhiguo Su, Ping Wang, Guanghui Ma, Songping Zhang.Ready-to-use hollow nanofibers membrane-based glucose testing strips. Analyst. 2014,   139(24): 6467-6473
[26]Zhan Zhou, Jing Zhang, Lijing Sun, Guanghui   Ma, Zhiguo Su. Comparison of site-specific pegylations on n-terminal of   interferon beta-1b: selectivity, efficiency, and in vivo/vitro   activity. Bioconjugate Chemistry, 2014, 25: 138-146
[27]Mengran   Yu, Yan Li, Songping Zhang, Xiunan Li, Yanli Yang, Yi Chen, Guanghui Ma,   Zhiguo Su. Improving stability of virus-like particles by ion-exchange   chromatographic supports with large pore size: advantages of gigaporous   media beyond enhanced binding capacity. J Chromatography A. 2014,   1331:69-79.
[28]Jiandong Cui, Lili Cui, Songping Zhang, Yufei   Zhang, Zhiguo Su, Guanghui Ma. Hybrid magnetic cross-linked enzyme   aggregates of phenylalanine ammonia lyase from Rhodotorula glutinis.   Plos One. 2014, 9(5): e97221 
[29]Zhidong Xiong, Weiqing Zhou,   Lijing Sun, Xiunan Li, Dawei Zhao, Yi Chen, Juan Li, Guanghui Ma, Zhiguo   Su. Konjac glucomannan microspheres for low-cost desalting of protein   solution. Carbohydrate Polymers. 2014, 111: 56-62
[30]Qingqing   Wang, Lijing Sun, Shaoyang Ji, Dawei Zhao, Jiaxin Liu, Zhiguo Su, Tao   Hu. Reversible protection of Cys-93(ß) by PEG alters the structural and   functional properties of the PEGylated hemoglobin. Biochimica Biophysica   Acta. 2014, 1844(7):1201-1207
[31]Fei Peng, Yongdong Liu, Xiunan   Li, Lijing Sun, Dawei Zhao, Qingqing Wang, Guanghui Ma, Zhiguo Su.   PEGylation of G-CSF in organic solvent markedly increases the efficacy   and reactivity through protein unfolding, hydrolysis inhibition and   solvent effect. J Biotechnology. 2014, 170: 42-49
[32]Bohm K,   Lijing Sun, Thakor D, Wirth M. Caveolin-1 limits human influenza A virus   (H1N1) propagation in mouse embryo-derived fibroblasts. Virology. 2014,   462-463C:241-253
[33]Dawei Zhao, Yongdong Liu, Yinjue Wang,   Xiunan Li, Qingqing Wang, Zhiguo Su. Membrane combined with hydrophilic   macromolecules enhancesprotein refolding at high concentration. Process   Biochemistry. 2014, 49: 1129-1134
[34]Ziqiang Wang, Yunshan Wang.   Hong Shi, Zhiguo Su. Improvement of the production efficiency of   L-(+)-tartaric acid by heterogeneous whole-cell bioconversion. Applied   Biochemistry & Biotechnology. 2014, 172: 3989-4001
[35]Panpan   Luan, Yanjun Jiang, Songping Zhang, Jing Gao, Zhiguo Su, Guanghui Ma,   Yufei Zhang. Chitosan-mediated formation of biomimetic silica   nanoparticles: An effective method for manganese peroxidase   immobilization and stabilization. J Bioscience Bioengineering. 2014,   118(5): 575-582 
[36]Chun Zhang, Yongdong Liu, Dawei Zhao, Xiunan   Li, Rong Yu, Zhiguo Su. Facile purification of Escherichia coli   expressed tag-free recombinant human tumor necrosis factor alpha from   supernatant. Protein Expression Purification. 2014, 95: 195-203
[37]Jiandong   Cui, Yan Li, Xiaoyan Ji, Bian HJ, Yufei Zhang, Zhiguo Su, Guanghui Ma,   Songping Zhang. Bio-sequestration of CO2 using carbonic anhydrase in   situ encapsulated inside electrospun hollow fibers. Chemical J Chinese   University, 2014, 35(9): 1999-2006 
[38]Feng Xiaoyi, Gao Fei, Qin   Peiyong, Ma Guanghui, Su Zhiguo, Ge Jia, Wang Ping*, Zhang Songping*.   Real time monitoring of on-chip coenzyme regeneration with SPR and DPI.   Analytical Chemistry. 2013, 85(4): 2370-2376. 
[39]Ku Zhiqiang, Ye   Xiaohua, Huang Xulin, Cai Yicun, Liu Qingwei, Li Yan, Su Zhiguo, Huang   Zhong*. Neutralizing antibodies induced by recombinant virus-like   particles of enterovirus 71 genotype C4 inhibit infection at pre- and   post-attachment steps. PLoS ONE. 2013, 8(2): 7601. 
[40]Wang Ziqiang, Wang Yunshan, Su Zhiguo*. Purification   and characterization of a cis-epoxysuccinic acid hydrolase from   Nocardia tartaricans CAS-52, and expression in Escherichia coli. Applied   Microbiology Biotechnology. 2013, 97: 2433-2441. 
[41]Zheng   Muqing, Su Zhiguo, Ji Xiaoyuan, Ma Guanghui, Wang Ping*, Zhang   Songping*. Magnetic field intensified bi-enzyme system with in situ   cofactor regeneration supported by magnetic nanoparticles. Journal of   Biotechnology. 2013, 168: 212-217. 
[42]Zheng Yingfu, Zhang   Songping, Miao Shida, Su Zhiguo*, Wang Ping*. Temperature sensitivity of   cellulase adsorption on lignin and its impact on enzymatic hydrolysis   of lignocellulosic biomass. Journal of Biotechnology. 2013, 166:   135-143. 
[43]Luo Jian, Zhou Weiqing, Su Zhiguo, Ma Guanghui, Gu   Tingyue*. Comparison of fully-porous beads and cored beads in size   exclusion chromatography for protein purification. Chemical Engineering   Science. 2013, 102: 99-105. 
[44]Miao Shida，Callow Nicholas, Zhang   Songping, Su Zhiguo, Wang Ping*, Liu Yongyan. Enzymatic synthesis of   oleic acid-based epoxy monomer for the production of value added   polymers. Biotechnology Letters. 2013, 35(6): 887-890. 
[45]Miao   Shida，Callow Nicholas, Wang Ping, Liu Youyan, Su Zhiguo, Zhang   Songping*. Soybean oil-based polyurethane networks: shape-memory effects   and surface morphologies. Journal of the American Oil Chemists'   Society. 2013, 90: 1415-1421. 
[46]Zhao Lan, Liu Yongdong, Wang   Yinjue, Huang Yongdong, Li Xiunan, Li Yan, Ma Guanghui, Su Zhiguo*.   Determination of leakage from antibody adsorbent: composition analysis   and pH effect. Biomed Chromatogr. 2013, 27(9): 1089-1091.
[47]Miao   Shida, Zhang Songping*, Su Zhiguo, Wang Ping. Synthesis of bio-based   polyurethanes from epoxidized soybean oil and isopropanolamine. Journal   of Applied Polymer Science. 2013, 127(3): 1929-1936. 
[48]李修乐，刘琳，高建萍，张竞，孔英俊，王明林，张贵锋，苏志国，PEG 化rhG-CSF 的修饰位点识别研究，药物生物技术，2013, 20(4): 348-352.
[49]刘祥玉，张贵锋，张羽飞，王 平，苏志国，马光辉，张松平.化学-酶催化法合成基于鱼鳞胶原蛋白的脂肽类表面活性剂及其在提高原油采收率中的应用. 过程工程学报. 2013, 13(4): 654-661.
[50]姬晓元，王 平，苏志国，马光辉，张松平.中空聚氨酯纳米纤维的制备与表征及其原位固定化酶的应用. 过程工程学报. 2013, 13(3): 481-487. 
[51]樊亚超，张松平，马光辉，周炜清，苏志国，张羽飞. 聚苯乙烯微球吸附脂肪酶催化油酸环氧化的研究。离子交换与吸附, 2013, 29(3): 200-210.
[52]刘祥玉，张贵锋，张羽飞，王 平，苏志国，马光辉，张松平.化学-酶催化法合成基于鱼鳞胶原蛋白的脂肽类表面活性剂及其在提高原油采收率中的应用. 过程工程学报. 2013, 13(4): 654-661.
[53]刁文锦，张松平，王平，周炜清，马光辉，苏志国，张羽飞. 超大孔微球固定化木瓜蛋白酶制备酵母抗氧化肽. 化学工程, 2013, 41(11): 1-4.
[54]周月芳，张焱，罗坚，康丽梅，陈毅，石红，孟庆雄，苏志国. 混合抗体的亲和色谱分离策略。色谱. 2013, 31(10): 974-979.
[55]冯翠，赵大伟，张纯，王健，秦培勇，刘永东，苏志国. 一种重组人睫状神经营养因子突变体的分离纯化及结构鉴定. 中国生物工程杂志，2013, 33(10): 21-27.
[56]康跻耀，张宁， 周炜清，孙李靖，张贵锋，马光辉，苏志国. 基于魔芋葡甘聚糖微球的胶原覆层型微载体的制备研究. 中国生物工程杂志，2013, 5(33): 44-49.
[57]张宁, 康跻耀, 高建萍, 王海燕, 孔英俊, 张贵锋, 苏志国. 胶原蛋白肽分子量对吸收过程的影响研究. 生物学杂志, 2013, 30(2): 10-13.
[58]刘琳, 李修乐, 高建萍, 孔英俊, 王明林, 张贵锋, 苏志国. 燕窝酶解产物中多肽的液相色谱质谱分析. 中国中药杂志 ，2013, 38(5): 714-719.
[59]李笑尘, 闫利华, 王智民, 张启伟, 高建萍, 陈两绵, 王锦玉, 仝燕, 张贵锋. 阿胶酶解物抗氧化肽的分离与质谱分析. 中国中药杂志，2013, 38(7): 18-22.
[60]王晓君, 刘新利, 李秀男, 马光辉, 苏志国. 低场核磁法测定凝胶过滤介质的孔径分布. 化工学报，2013, 64(11): 4090-95.
[61]Wang   Peng, Wang Yunshan, Liu Yongdong, Shi Hong, Su Zhiguo, Novel in situ   product removal technique for simultaneous production of propionic acid   and vitamin B12 by expanded bed adsorption bioreactor. Bioresource   Technology, 2012, 104: 652-659. (IF 5.352)
[62]Peng Fei, Wang   Yinjue, Sun lijing, Liu Yongdong, Hu Tao, Zhang Guifeng, Ma Gaunghui, Su   Zhiguo. PEGylation of Proteins in Organic Solution: A Case Study for   Interferon beta-1b. Bioconjugate Chemistry. Bioconjugate Chem. 2012, 23:   1812−1820.（IF5.224）
[63]Wang Ziqiang, Wang Yunshan, Shi Hong, Su   Zhiguo. Expression and production of recombinant cis-epoxysuccinate   hydrolase in Escherichia coli under the control of temperature-dependent   promoter. Journal Biotechnology, 2012, 162: 232-236. (IF 3.288)
[64]Wang   Peng, Wang Yunshan, Su Zhiguo. Microbial production of propionic acid   with Propionibacterium freudenreichii using an anion exchanger-based in   situ product recovery (ISPR) process with direct and indirect contact of   cells. Applied Biochemistry Biotechnology. 2012, 166: 974-986. (IF   1.998)
[65]Wang Peng, Wang Yunshan, Su Zhiguo. Improvement of   adenosylcobalamin production by metabolic control strategy in   Propionibacterium freudenreichii. Applied Biochemistry Biotechnology.   2012, 167: 62-72. (IF 1.998)
[66]Ding Fei, Li Xiu-Nan, Diao   Jian-Xiong, Sun Ye, Zhang Li, Sun Ying. Chiral recognition of metalaxyl   enantiomers by human serum albumin: evidence from molecular modeling and   photophysical approach. Chirality. 2012, 24(6):471-480. (IF 2.232)
[67]Ding   Fei, Li Xiu-Nan, Diao Jian-Xiong, Sun Ye, Zhang Li, Ma Lin, Yang   Xin-Ling, Zhan g Li, Sun Ying. Potential toxicity and affinity of   triphenylmethane dye malachite green to lysozyme. Ecotoxicology and   Environmental Safety. 2012, 78: 41-49. (IF 2.617)
[68]Ding Fei,   Zhang Li, Diao Jian-Xiong, Li Xiu-Nan, Ma Lin, Sun Ying. Human serum   albumin stability and toxicity of anthraquinone dye alizarin complexone:   An albumin–dye model. Ecotoxicology and Environmental Safety. 2012, 79:   238-246. (IF 2.617)
[69]Fei Ding, Ye Sun, Jian-Xiong Diao,   Xiu-Nan Li, Xin-Ling Yang, Ying Sun, Li Zhang. Features of the complex   of food additive hesperidin to hemoglobin. Journal of Photochemistry and   Photobiology B: Biology, 2012, 106: 53-60. (IF 2.650)
[70]Zhang   Guishan, Zhang Fan, Ding Gang, Li Jie, Guo Xiaopeng, Zhu Jinxing, Zhou   Liguang, Cai Shichun, Liu Xiaoli, Luo Yuanming, Zhang Guifeng, Shi   Wenyuan, Dong Xiuzhu. Acyl homoserine lactone-based quorum sensing in a   methanogenic archaeon. The ISME Journal. 2012, 7(6):1336-1344. （IF7.375）
[71]Zou   Shuping, Xie Luping, Liu Yanli, Kaleem Imdad, Zhang Guifeng, Li Chun.   N-linked glycosylation influences on the catalytic and biochemical   properties of Penicillium purpurogenum -D-glucuronidase. Journal   Biotechnology, 2012, 157: 399-404. (IF 3.288)
[72]Wang Jun, Wang   Yinjue, Hu Tao, Li Xiunan, Huang Yongdong, Liu Yongdong, Ma Guanghui, Su   Zhiguo. An oriented adsorption strategy for efficient solid phase   PEGylation of recombinant staphylokinase by immobilized metal-ion   affinity chromatography. Process Biochemistry. 2012, 47: 106–112. (IF   3.225)
[73]马洪梅，张贵锋，李春，孔英俊，高飞，胡涛，马光辉，苏志国. 界面上配基种类对BSA吸附行为的影响. 中国生物工程杂志.  2012, 32(7):53-59.
[74]冯静，黄孟军，张贵锋，孔英俊，高建萍，黄永东，苏志国. 亲和层析介质上蛋白质偶联位点的控制方法. 过程工程学报.  2012, 12(2): 277-282.
[75]康丽梅，张焱，罗坚，李由，周月芳，余蓉，苏志国. 超大孔离子交换制备色谱分离纯化高活性凝血因子VIII. 色谱.  2012, 30(6): 618-623.
[76]初歆, 王鹏, 王云山, 苏志国. 玉米秸秆酶解液发酵生产丙酸联产益生菌. 中国饲料. 2012, 8: 27-30. 
[77]Zhidan   Liu, Jing Liu, Songping Zhang, Xin-Hui Xing, Zhiguo Su. Microbial fuel   cell based biosensor for in situ monitoring of anaerobic digestion   process. Bioresource Technology, 2011, 102(22):10221-10229
[78]Jun   Wang, Tao Hu, Yongdong Liu, Guifeng Zhang, Guanghui Ma, Zhiguo Su.   Kinetic and stoichiometric analysis of the modification process for   N-terminal PEGylation of staphylokinase. Analytical Biochemistry, 2011,   412: 114-116
[79]Lan Zhao，Yongdong Liu，Yongdong Huang， Xiunan   Li，Yinjue Wang，Yan Li， Guanghui Ma，Zhiguo Su. Deliberate manipulation of   the surface hydrophobicity of an adsorbent for an efficient   purification of a giant molecule with multiple subunits. Journal of   Separation Science, 2011, 34, 3186-3193
[80]Yingjun Kong, Guifeng   Zhang, Jian Luo, Yongdong Liu, Xiunan Li, Guanghui Ma, Yalin Zhao,   Sanping Yuan and Zhiguo Su. Facile purification and characterization of   recombinant human antithrombin III from transgenic goat milk. J Chem   Technol Biotechnol, 2011, 86: 1303–1309
[81]Chunyang Zheng,   Zhanyong Zhao, Yan Li, Lin Wang, Zhiguo Su. Effect of IPTG amount on   apo- and holo- forms of glycerophosphate oxidase expressed in   Escherichia coli. Protein Expression and Purification, 2011,   75(2)：133-137
[82]Tao Liu, Guifeng Zhang, Suping Li, Yinjue Wang,   Guanghui Ma and Zhiguo Su. Analysis of gelatin plasma substitutes in   blood based on detection of hydroxyproline derivatives. Artificial   Cells, Blood Substitutes and Biotechnology, 2011, 39(1): 19-25
[83]Lijing   Sun, Yongdong Huang, Yan Zhang, Qingqiang Meng, Jian Luo, Bei Fan,   Guanghui Ma and Zhiguo Su. A Simple and Rapid Procedure for Purification   of Haptoglobin from Human Plasma Fraction IV. Artificial Cells Blood   Substitutes and Biotechnology. 2011, 39(2):79-86
[84]李由，张焱，苏海佳，罗坚，白倩，马光辉，苏志国. 乳腺生物反应器表达的重组人乳清白蛋白的快速纯化工艺. 中国生物工程杂志, 2011，31(8): 66-72
[85]孙西艳，张焱，罗坚，李岩，马光辉，苏志国. 乳腺生物反应器表达产物层析分离过程中介质的污染机理及其再生策略. 生物工程学报, 2011, 27(11): 1645-1654
[86]高建萍，刘琳，张贵锋，王明林，黄永东，刘永东，苏志国. 多级逆流固液提取技术提取大豆分离蛋白. 过程工程学报, 2011，11(2)：312-317

授权和申请发明专利（近5年）

[1] 张竞，苏志国，刘强，窦婧，马光辉，一种异端基双官能团烷基醚类化合物及其用途，ZL20121014394.5
[2] 张竞，周展，苏志国，马光辉，聚乙二醇修饰的重组人干扰素β-1b及其制备方法，ZL201310066150.8
[3] 李秀男，苏志国，电极清洗、校正和保存装置及方法，ZL201310062061.6
[4] 李秀男，苏志国，一种多参数一体化色谱流通池，ZL201310088098.6
[5] 李秀男，苏志国，一种多功能的通用阀，ZL201310062077.7
[6] 李秀男，沈志刚，苏志国，崔万臣，生物技术药物高效纯化分析系统及其药物分离检测方法，ZL201310198644.1
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